Alli

Active Ingredients:

• Orlistat

How does Alli work and what pharmaceutical group does it belong to?

The preparation Alli contains the active ingredient called Orlistat a substance that inactivates gastrointestinal enzymes. The inactivation of GI enzymes leads to inability to hydrolyze triglycerides thus the absorption of fats is inhibited. The preparation does not require systemic absorption and works in the GI tract.

Which conditions are treated with Orlistat?

The preparation is indicated in treatment of obesity alongside moderate physical exercise.

What should a patient know before using Alli?

Orlistat should not be used in cases of:

• Hypersensitivity
• Chronic malabsorption syndrome
• Cholestasis
• Young age
• Hyperoxaluria
• Nephrolithiasis

Which adverse effects may manifest when using the medication?

The side effects of Alli include:

• Gastrointestinal tract: oily stool, meteorism, imperative defecation, frequent defecation, stool incontinence, nausea, vomiting, infectious diarrhea, gum and teeth disease
• CNS: headache, dizziness, fatigability, insomnia, anxiety, depression
• Respiratory system: upper respiratory tract infections, ENT infections, otitis
• Urogenital tract: non-regular menstrual cycle, vaginitis, urogenital infections
• Locomotor tract: back pain, lower extremities pain, arthritis, myalgia, joint fracture, tendinitis
• Skin: rash, dry skin
• Other: flu, feet swelling
• Allergic reactions

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Orlistat?

The drug is affected by the following:

• Immunosuppressors
• Vitamins

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient: Orlistat is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.